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          • Primary Antibodies ›
          • RFC4 Antibodies

          Invitrogen

          RFC4 Polyclonal Antibody

          Advanced Verification
          View all (16) RFC4 antibodies

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          Cite RFC4 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          • Advanced Verification (1)
          RFC4 Antibody in Immunocytochemistry (ICC/IF)
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          RFC4 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          RFC4 Antibody (PA5-83954) in ICC/IF

          Immunofluorecent analysis of RFC4 in human cell line U-2 OS using RFC4 Polyclonal Antibody (Product # PA5-83954). Staining shows localization to nucleoplasm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          RFC4 Antibody in Immunocytochemistry (ICC/IF)
          RFC4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RFC4 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RFC4 Antibody in Western Blot (WB)
          RFC4 Antibody
          RFC4 Polyclonal Antibody

          Product Details

          PA5-83954

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human RFC4. Recombinant protein control fragment (Product #RP-104105).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.4 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2791106

          Product Specific Information

          Immunogen sequence: RIIEPLTSRC SKFRFKPLSD KIQQQRLLDI AKKENVKISD EGIAYLVKVS EGDLRKAITF LQSATRLTGG KEITEKVITD IAGVIP

          Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 91%.

          Target Information

          Human Replication Factor C (RFC) is a hetero-pentameric protein consisting of the p140, p40, p38, p37 and p36 subunits. RFC functions in the loading of the DNA polymerase delta processivity factor (PCNA, Proliferating Cell nuclear Antigen) onto a primed DNA template during DNA synthesis and repair. RFC may also participate in the DNA damage checkpoint response with a PCNA-like hetero-trimer consisting of Hus 1, Rad 1 and Rad 9.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: A1 37 kDa subunit; Activator 1 37 kDa subunit; Activator 1 subunit 4; replication factor C (activator 1) 4, 37kDa; Replication factor C 37 kDa subunit; Replication factor C subunit 4; RF-C 37 kDa subunit; RFC 37 kDa subunit; RFC p37; RFC4; unnamed protein product

          View more View less

          Gene Aliases: A1; MRMNS; RFC37; RFC4

          View more View less

          UniProt ID: (Human) P35249

          View more View less

          Entrez Gene ID: (Human) 5984

          View more View less

          Function(s)
          nucleotide binding DNA binding DNA clamp loader activity protein binding ATP binding ATPase activity single-stranded DNA-dependent ATP-dependent DNA helicase activity enzyme binding
          Process(es)
          DNA replication DNA-dependent DNA replication DNA strand elongation involved in DNA replication DNA repair positive regulation of DNA-directed DNA polymerase activity
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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