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Invitrogen
CNGA3 Polyclonal Antibody
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Product Details
PA5-83962
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CNGA3. Recombinant protein control fragment (Product #RP-108383).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FLLRRWAARH VHHQDQGPDS FPDRFRGAEL KEVSSQESNA QANVGSQEPA DRGRSAWPLA KCNTNTSNNT EEEK
Highest antigen sequence indentity to the following orthologs: Rat - 49%, Mouse - 45%.
Target Information
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cng channel; CNG channel alpha-3; CNG-3; CNGalpha2; cone photoreceptor cGMP-gated channel alpha subunit; cone photoreceptor cGMP-gated channel subunit alpha; Cone photoreceptor cGMP-gated channel subunit alpha-3; cyclic nucleotide gated channel alpha 3; cyclic nucleotide-gated cation channel alpha-3; Cyclic nucleotide-gated channel alpha-3; unnamed protein product
Gene Aliases: ACHM2; CCNC1; CCNCa; CCNCalpha; CNCG3; CNG3; CNGA3
UniProt ID: (Human) Q16281
Entrez Gene ID: (Human) 1261
nucleotide binding
ion channel activity
intracellular cyclic nucleotide activated cation channel activity
intracellular cAMP activated cation channel activity
intracellular cGMP activated cation channel activity
calcium channel activity
sodium channel activity
protein binding
ligand-gated ion channel activity
myosin binding
cGMP binding
cadherin binding
ion transport
cation transport
sodium ion transport
calcium ion transport
signal transduction
visual perception
response to magnesium ion
ion transmembrane transport
sodium ion transmembrane transport
response to cAMP
transmembrane transport
retina development in camera-type eye
calcium ion transmembrane transport
cation transmembrane transport
inorganic cation import across plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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