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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • CD229 (Ly9) Antibodies

          Invitrogen

          CD229 Polyclonal Antibody

          View all (26) CD229 (Ly9) antibodies

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          Cite CD229 Polyclonal Antibody

          • Antibody Testing Data (2)
          CD229 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          CD229 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          CD229 Antibody (PA5-84036) in IHC (P)

          Immunohistochemical analysis of CD229 in human kidney using CD229 Polyclonal Antibody (Product # PA5-84036) shows strong membranous positivity in cells in tubules. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          CD229 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          CD229 Antibody in Western Blot (WB)
          CD229 Polyclonal Antibody

          Product Details

          PA5-84036

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:1,000-1:2,500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human LY9. Recombinant protein control fragment (Product #RP-101244).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.6 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2791188

          Product Specific Information

          Immunogen sequence: KRKGRCSVPA FCSSQAEAPA DTPEPTAGHT LYSVLSQGYE KLDTPLRPAR QQPTPTSDSS SDSNLTTEED EDRPEVHKPI SGRYE

          Highest antigen sequence indentity to the following orthologs: Mouse - 48%, Rat - 48%.

          Target Information

          CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: CD229; Cell surface molecule Ly-9; Lymphocyte antigen 9; RP11-312J18.1; Signaling lymphocytic activation molecule 3; SLAM family member 3; SLAMF3; T-lymphocyte surface antigen Ly-9

          View more View less

          Gene Aliases: CD229; CDABP0070; hly9; LY9; mLY9; SLAMF3

          View more View less

          UniProt ID: (Human) Q6P2J4

          View more View less

          Entrez Gene ID: (Human) 4063

          View more View less

          Function(s)
          molecular_function immunoglobulin receptor superfamily
          Process(es)
          positive regulation of interleukin-17 production innate immune response T-helper 17 cell lineage commitment
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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