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Invitrogen
PKC eta Polyclonal Antibody
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Product Details
PA5-84168
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PRKCH. Recombinant protein control fragment (Product #RP-103167).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DHFVANCTLQ FQELLRTTGA SDTFEGWVDL EPEGKVFVVI TLTGSFTEAT LQRDRIFKHF TRKRQRAMRR RVHQ
Highest antigen sequence indentity to the following orthologs: Mouse - 97%, Rat - 97%.
Target Information
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC26269; MGC5363; nPKC-eta; PKC-L; Protein kinase C eta type; Protein uPEP2; unnamed protein product
Gene Aliases: nPKC-eta; PKC-L; PKCL; PRKCH; PRKCL; uORF2
UniProt ID: (Human) P24723
Entrez Gene ID: (Human) 5583
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
calcium-independent protein kinase C activity
protein kinase inhibitor activity
protein binding
ATP binding
zinc ion binding
kinase activity
transferase activity
enzyme binding
protein serine/threonine kinase inhibitor activity
small GTPase binding
translation regulator activity
metal ion binding
protein serine kinase activity
protein serine/threonine kinase binding
regulation of translation
protein phosphorylation
signal transduction
positive regulation of macrophage derived foam cell differentiation
negative regulation of translation
cell differentiation
positive regulation of translation in response to stress
cellular response to amino acid starvation
negative regulation of glial cell apoptotic process
intracellular signal transduction
positive regulation of keratinocyte differentiation
positive regulation of B cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
positive regulation of glial cell proliferation
phospholipase C/protein kinase C signal transduction
positive regulation of protein localization to plasma membrane
regulation of bicellular tight junction assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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