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Invitrogen
p38 MAPK gamma Polyclonal Antibody
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Product Details
PA5-84209
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MAPK12. Recombinant protein control fragment (Product #RP-103189).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FKGSDHLDQL KEIMKVTGTP PAEFVQRLQS DEAKNYMKGL PELEKKDFAS ILTNASPLAV
Highest antigen sequence indentity to the following orthologs: Rat - 88%, Mouse - 87%.
Target Information
MAPK12 (p38 gamma) is a serine/threonine kinase involved in many different cellular processes. It is activated during hypoxia and gamma-irradiation-induced G(2) arrest. Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. MAPK12 functions as a signal transducer during differentiation of myoblasts to myotubes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ERK-6; ERK5; Extracellular signal-regulated kinase 6; MAP kinase 12; MAP kinase p38 gamma; MAPK12; Mitogen-activated protein kinase 12; mitogen-activated protein kinase 3; Mitogen-activated protein kinase p38 gamma; OTTHUMP00000196671; Stress-activated protein kinase 3; unnamed protein product
Gene Aliases: ERK-6; ERK3; ERK6; MAPK 12; MAPK12; P38GAMMA; PRKM12; SAPK-3; SAPK3
UniProt ID: (Human) P53778
Entrez Gene ID: (Human) 6300
MAPK cascade
signal transduction
muscle organ development
cellular response to stress
intracellular signal transduction
signal transduction in response to DNA damage
myoblast differentiation
negative regulation of cell cycle
positive regulation of muscle cell differentiation
regulation of cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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