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Invitrogen
SFTPD Polyclonal Antibody
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FIGURE: 1 / 7
SFTPD Antibody (PA5-84308) in IHC (P)
Immunohistochemistry analysis of SFTPD in human cerebral cortex, kidney, lung and lymph node. Samples were incubated with SFTPD polyclonal antibody (Product # PA5-84308). Shows similar protein distribution across tissues to independent SFTPD antibody (Product # PA5-83727) (B).
Product Details
PA5-84308
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SFTPD. Recombinant protein control fragment (Product #RP-103269).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF
Highest antigen sequence indentity to the following orthologs: Mouse - 77%, Rat - 77%.
Target Information
Surfactant protein D (SP-D) is synthesized and secreted by lung epithelial cells. It belongs to group III of the family of C-type lectins and members of this group has overall structure consisting of multiple globular 'head' regions linked by triple-helical, collagen-like, strands. This group also includes SP-A and the serum proteins mannan-binding protein, conglutinin and collectin-43, all of which have been shown to bind to the C1q receptor found on a wide variety of cells. Both SP-D and SP-A have been shown to enhance oxygen radical production by alveolar macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Collectin-7; Collectin7; Lung surfactant protein D; PSP-D; PSP-D Surfactant protein D; pulmonary surfactant apoprotein; Pulmonary surfactant associated protein PSP-D; Pulmonary surfactant-associated protein D; SFTP 4; Surfactant associated protein pulmonary 4; surfactant-associated protein, pulmonary 4
Gene Aliases: COLEC7; PSP-D; PSPD; SFTP4; SFTPD; SP-D
UniProt ID: (Human) P35247
Entrez Gene ID: (Human) 6441
regulation of cytokine production
receptor-mediated endocytosis
respiratory gaseous exchange
negative regulation of T cell proliferation
defense response to bacterium
surfactant homeostasis
cellular protein metabolic process
negative regulation of interleukin-2 biosynthetic process
innate immune response
macrophage chemotaxis
lung alveolus development
positive regulation of phagocytosis
regulation of immune response
reactive oxygen species metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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