Search
Invitrogen
Drebrin Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 6
Drebrin Antibody (PA5-84319) in IHC (P)
Immunohistochemistry analysis of Drebrin in human cerebral cortex, kidney, liver and testis. Samples were incubated with Drebrin polyclonal antibody (Product # PA5-84319). Shows similar protein distribution across tissues to independent Drebrin antibody (Product # PA5-84067) (B).
Product Details
PA5-84319
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DBN1. Recombinant protein control fragment (Product #RP-103282).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: CACASHVAKV AEFFQGVDVI VNASSVEDID AGAIGQRLSN GLARLSSPVL HRLRLREDEN AEPVGTTYQK TDAAVEMKRI NREQFWEQ
Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Developmentally-regulated brain protein; DKFZp434D064; Drebrin; drebrin A; drebrin E; drebrin E2; unnamed protein product
Gene Aliases: D0S117E; DBN1
UniProt ID: (Human) Q16643
Entrez Gene ID: (Human) 1627
in utero embryonic development
actin filament organization
nervous system development
cell communication by chemical coupling
cell communication by electrical coupling
cell differentiation
positive regulation of synaptic plasticity
maintenance of protein location in cell
regulation of neuronal synaptic plasticity
generation of neurons
regulation of dendrite development
positive regulation of dendritic spine morphogenesis
neural precursor cell proliferation
positive regulation of receptor localization to synapse
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support