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Invitrogen
RRM2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-84324
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RRM2. Recombinant protein control fragment (Product #RP-99902).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LAPITDPQQL QLSPLKGLSL VDKENTPPAL SGTRVLASKT ARRIFQEPTE PKTKAAAPGV EDEPLLRE
Highest antigen sequence indentity to the following orthologs: Mouse - 72%, Rat - 68%.
Target Information
RRM2 is one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the protein (M2) is regulated in a cell-cycle dependent fashion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ribonucleotide reductase M2 polypeptide; ribonucleotide reductase small chain; ribonucleotide reductase small subunit; RRR2M; uncharacterized protein C2orf48; unnamed protein product
Gene Aliases: C2orf48; R2; RR2; RR2M
UniProt ID: (Human) P31350
Entrez Gene ID: (Human) 6241
dTMP biosynthetic process
DNA repair
ribonucleoside diphosphate metabolic process
deoxyribonucleotide biosynthetic process
2'-deoxyribonucleotide biosynthetic process
protein heterotetramerization
positive regulation of G1/S transition of mitotic cell cycle
positive regulation of mitotic cell cycle phase transition
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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