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Invitrogen
LIPA Polyclonal Antibody
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Product Details
PA5-84326
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LIPA. Recombinant protein control fragment (Product #RP-103288).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: FALGPVASVA FCTSPMAKLG RLPDHLIKDL FGDKEF
Highest antigen sequence indentity to the following orthologs: Mouse - 56%, Rat - 64%.
Target Information
This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Acid cholesteryl ester hydrolase; cholesterol ester hydrolase; Cholesteryl esterase; Diacylglycerol lipase; Lipase A; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase; Lysosomal acid lipase/cholesteryl ester hydrolase; RP11-341B24.1; Sterol esterase; Triacylglycerol ester hydrolase; Triacylglycerol lipase; unnamed protein product
Gene Aliases: CESD; LAL; LIPA
UniProt ID: (Human) P38571
Entrez Gene ID: (Human) 3988
mitotic cell cycle
cell morphogenesis
retinoid metabolic process
liver development
endothelial cell proliferation
response to dietary excess
hematopoietic progenitor cell differentiation
acute inflammatory response
respiratory burst involved in inflammatory response
glucose metabolic process
glycolytic process
lipid metabolic process
fatty acid metabolic process
neutral lipid metabolic process
triglyceride metabolic process
cholesterol biosynthetic process
ATP biosynthetic process
vitamin A metabolic process
endocytosis
inflammatory response
mitochondrion organization
lysosome organization
small GTPase mediated signal transduction
cholesterol metabolic process
cell proliferation
endosome to lysosome transport
determination of adult lifespan
lipid biosynthetic process
response to cold
response to xenobiotic stimulus
gene expression
cholesterol storage
programmed cell death
lipid catabolic process
sterol metabolic process
lipid storage
hemopoiesis
myeloid cell differentiation
T cell differentiation
cholesterol transport
lung development
defecation
TOR signaling
myeloid cell apoptotic process
response to vitamin A
cholesterol efflux
response to lipid
low-density lipoprotein particle clearance
common myeloid progenitor cell proliferation
T cell proliferation
lipoprotein catabolic process
regulation of membrane potential
spleen development
bone marrow development
tissue remodeling
multicellular organismal homeostasis
homeostasis of number of cells
homeostasis of number of cells within a tissue
epithelial cell proliferation
positive regulation of T cell receptor signaling pathway
regulation of mitochondrial membrane potential
lipid homeostasis
adipose tissue development
blood vessel endothelial cell differentiation
macrophage homeostasis
T cell apoptotic process
fat cell proliferation
triglyceride-rich lipoprotein particle clearance
cell proliferation in bone marrow
liver morphogenesis
energy homeostasis
lipid import into cell
multicellular organismal-level chemical homeostasis
response to rapamycin
reactive oxygen species biosynthetic process
adaptive thermogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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