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Invitrogen
eIF2b epsilon Polyclonal Antibody
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Product Details
PA5-84639
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human EIF2B5. Recombinant protein control fragment (Product #RP-107331).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SILEENVLLG SGTVIGSNCF ITNSVIGPGC HIGDNVVLDQ TYLWQGVRVA AGAQIHQSLL CDNAEVKERV TLKPRSVLTS QVVVGPNITL PEGSVISLHP PD
Highest antigen sequence indentity to the following orthologs: Mouse - 90%, Rat - 88%.
Target Information
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B, a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: eIF-2B GDP-GTP exchange factor subunit epsilon; eIF2B GDP-GTP exchange factor subunit epsilon; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; Translation initiation factor eIF2B subunit epsilon
Gene Aliases: CACH; CLE; EIF-2B; EIF2B5; EIF2BE; EIF2Bepsilon; LVWM
UniProt ID: (Human) Q13144
Entrez Gene ID: (Human) 8893
ovarian follicle development
translational initiation
aging
response to heat
response to glucose
astrocyte development
oligodendrocyte development
negative regulation of translational initiation in response to stress
response to endoplasmic reticulum stress
cellular response to drug
myelination
response to peptide hormone
positive regulation of GTPase activity
positive regulation of translational initiation
astrocyte differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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