Search
Invitrogen
ANAPC2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
PA5-84731
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human ANAPC2. Recombinant protein control fragment (Product #RP-105397).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: REEVHTMLRG VLFFSTPRTF QEMIQRLYGC FLRVYMQSKR KGEGGTDPEL EGELDSRYAR RRYYRLLQSP LCAGCSSDKQ QCWCR
Highest antigen sequence indentity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Anaphase-promoting complex subunit 2; APC2; Cyclosome subunit 2; unnamed protein product
Gene Aliases: ANAPC2; APC2; KIAA1406
UniProt ID: (Human) Q9UJX6
Entrez Gene ID: (Human) 29882
ubiquitin-dependent protein catabolic process
metaphase/anaphase transition of mitotic cell cycle
regulation of mitotic cell cycle
nervous system development
proteasomal protein catabolic process
negative regulation of gene expression
protein ubiquitination
cell differentiation
anaphase-promoting complex-dependent catabolic process
positive regulation of synaptic plasticity
positive regulation of axon extension
positive regulation of dendrite morphogenesis
cell division
regulation of meiotic cell cycle
protein K48-linked ubiquitination
protein K11-linked ubiquitination
positive regulation of synapse maturation
protein branched polyubiquitination
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support