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Invitrogen
PIK3R2 Polyclonal Antibody
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Product Details
PA5-84807
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PI3K p85 beta. Recombinant protein control fragment (Product #RP-105468).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EMQRILLNSE RLKSRIAEIH ESRTKLEQQL RAQASDN
Highest antigen sequence indentity to the following orthologs: Rat - 97%, Mouse - 97%.
Target Information
Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K; PI3K regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta
Gene Aliases: MPPH; MPPH1; p85; p85-BETA; P85B; PIK3R2
UniProt ID: (Human) O00459
Entrez Gene ID: (Human) 5296
GTPase activator activity
protein binding
1-phosphatidylinositol-3-kinase activity
protein phosphatase binding
receptor tyrosine kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity
kinase modulator
cellular glucose homeostasis
phosphatidylinositol biosynthetic process
insulin receptor signaling pathway
regulation of autophagy
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
protein transport
cellular response to insulin stimulus
response to endoplasmic reticulum stress
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of transcription factor import into nucleus
positive regulation of GTPase activity
regulation of phosphatidylinositol 3-kinase activity
positive regulation of transcription from RNA polymerase II promoter
phosphatidylinositol phosphorylation
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
T cell receptor signaling pathway
leukocyte migration
regulation of small GTPase mediated signal transduction
positive regulation of glucose import in response to insulin stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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