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Invitrogen
PAIP1 Polyclonal Antibody
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Product Details
PA5-84934
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PAIP1. Recombinant protein control fragment (Product #RP-108620).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GTNGQVTRAD ILQVGLRELL NALFSNPMDD NLICAVKLLK LTGSVLEDAW KEKGKMDMEE IIQRIENVVL DANCSRDVKQ MLLK
Highest antigen sequence indentity to the following orthologs: Mouse - 98%, Rat - 98%.
Target Information
The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PABC1-interacting protein 1; PABP-interacting protein 1; PAIP-1; Polyadenylate-binding protein-interacting protein 1; similar to central domain of eukaryotic initiation factor 4G
Gene Aliases: PAIP1
UniProt ID: (Human) Q9H074
Entrez Gene ID: (Human) 10605
translational initiation
regulation of translation
regulation of translational initiation
positive regulation by host of viral process
mRNA stabilization
CRD-mediated mRNA stabilization
negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
positive regulation of cytoplasmic translation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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