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Invitrogen
SLC27A1 Polyclonal Antibody
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Product Details
PA5-85002
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC27A1. Recombinant protein control fragment (Product #RP-108661).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QREGFDPRQT SDRLFFLDLK QGHYLPLNEA VYTRICSGAF
Highest antigen sequence indentity to the following orthologs: Rat - 83%, Mouse - 80%.
Target Information
SLC27A1 is a protein coding gene. Mediates the ATP-dependent import of long-chain fatty acids (LCFA) into the cell by mediating their translocation at the plasma membrane. Has also an acyl-CoA ligase activity for long-chain and very-long-chain fatty acids. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane-associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ACSVL5FATP-1; Arachidonate--CoA ligase; EC 6.2.1; FATP-1; Fatty acid transport protein 1; FLJ00336; Long-chain fatty acid transport protein 1; Long-chain-fatty-acid--CoA ligase; MGC71751; solute carrier family 27 (fatty acid transporter), member 1; Solute carrier family 27 member 1; unnamed protein product; Very long-chain acyl-CoA synthetase
Gene Aliases: ACSVL5; FATP; FATP-1; FATP1; SLC27A1
UniProt ID: (Human) Q6PCB7
Entrez Gene ID: (Human) 376497
nucleotide binding
long-chain fatty acid-CoA ligase activity
long-chain fatty acid transporter activity
protein binding
biotin transporter activity
fatty acid transporter activity
efflux transmembrane transporter activity
ligase activity
very long-chain fatty acid-CoA ligase activity
identical protein binding
protein serine/threonine kinase activator activity
arachidonate-CoA ligase activity
oleoyl-CoA ligase activity
medium-chain fatty acid transport
long-chain fatty acid metabolic process
lipid metabolic process
fatty acid metabolic process
lipid transport
response to cold
positive regulation of triglyceride biosynthetic process
biotin transport
fatty acid transport
long-chain fatty acid transport
plasma membrane long-chain fatty acid transport
positive regulation of heat generation
response to insulin
adiponectin-activated signaling pathway
glucose import in response to insulin stimulus
long-chain fatty acid import
export across plasma membrane
transport across blood-brain barrier
biotin import across plasma membrane
lipid transport across blood brain barrier
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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