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Invitrogen
OLFM4 Polyclonal Antibody
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Product Details
PA5-85041
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human OLFM4. Recombinant protein control fragment (Product #RP-108295).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KLVIQLKESF GGSSEIVDQL EVEIRNMTLL VEKLETLDKN NVLAIRREIV ALKTKLKECE ASKDQNTPVV HPPPTPGSCG HGGVVN
Highest antigen sequence indentity to the following orthologs: Mouse - 54%, Rat - 77%.
Target Information
OLFM4 is a 510 amino acid extracellular matrix glycoprotein belonging to the olfactomedin-related protein family and found to be selectively expressed in inflammed colonic epithelium. It has one signal peptide, six N-linked glycosylation motif and forms disulfide-bonded multimers. OLFM4 a transcription factor may have a matrix-related function in differentiation. Constitutively expressed OLFM4 in cancer cells binds to the potent apoptosis inducer GRIM-19 and has a novel antiapoptotic action and hence might serve as a diagnostic marker for human cancers. Reports suggest that OLFM4 promotes proliferation of PANC-1 cells by favoring transition from the S to G2/M phase. Potential interaction of OLFM4 with endogenous cell surface lectins and cadherins may mediate cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Antiapoptotic protein GW112; G-CSF-stimulated clone 1 protein; hGC-1; hOLfD; olfactoimedin; Olfactomedin-4; OLM4; tiarin; unnamed protein product
Gene Aliases: bA209J19.1; GC1; GW112; hGC-1; hOLfD; OlfD; OLFM4; OLM4; pDP4; UNQ362; UNQ362/PRO698
UniProt ID: (Human) Q6UX06
Entrez Gene ID: (Human) 10562
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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