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Invitrogen
MYO15A Polyclonal Antibody
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Product Details
PA5-85061
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MYO15A. Recombinant protein control fragment (Product #RP-108704).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LHPHLTRFLQ DVSRTPGLPF QGIAKACEQN LQKTLRFGGR LELPSSIELR AMLAGRSSKR QLFLLPGGLE RHLKIKTCTV ALDVVEEICA EMA
Highest antigen sequence indentity to the following orthologs: Rat - 87%, Mouse - 86%.
Target Information
This gene encodes an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: myosin-XV; Unconventional myosin-15; Unconventional myosin-XV
Gene Aliases: DFNB3; MYO15; MYO15A
UniProt ID: (Human) Q9UKN7
Entrez Gene ID: (Human) 51168
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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