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Invitrogen
SEC24A Polyclonal Antibody
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FIGURE: 1 / 6
SEC24A Antibody (PA5-100110) in ICC/IF
Immunofluorescent analysis of SEC24A in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and SEC24A polyclonal antibody (Product # PA5-100110) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100110
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SEC24A(Accession O95486), corresponding to amino acid residues P469-T519.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SEC24A.
Target Information
SC24A is a component of coat protein II (COPII; see MIM 601924)-coated vesicles that mediate protein transport from the endoplasmic reticulum. SEC24A is 1 of several mammalian proteins that show structural and functional homology to yeast Sec24.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SEC24 family, member A; SEC24 homolog A, COPII coat complex component; SEC24 related gene family, member A; SEC24-related protein A; unnamed protein product
UniProt ID: (Human) O95486, (Mouse) Q3U2P1
Entrez Gene ID: (Human) 10802, (Rat) 287275, (Mouse) 77371
intracellular protein transport
ER to Golgi vesicle-mediated transport
positive regulation of protein exit from endoplasmic reticulum
cargo loading into COPII-coated vesicle
positive regulation of ER to Golgi vesicle-mediated transport
regulation of cholesterol transport
cholesterol homeostasis
positive regulation of protein secretion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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