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Invitrogen
NELL1 Polyclonal Antibody
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FIGURE: 1 / 3
NELL1 Antibody (PA5-100288) in ICC/IF
Immunofluorescent analysis of NELL1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and NELL1 polyclonal antibody (Product # PA5-100288) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100288
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NELL1(Accession Q92832), corresponding to amino acid residues A612-G662.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total NELL1.
Target Information
This gene encodes a cytoplasmic protein that contains epidermal growth factor (EGF)-like repeats. The encoded heterotrimeric protein may be involved in cell growth regulation and differentiation. A similar protein in rodents is involved in craniosynostosis. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: nel homolog; NEL-like 1; NEL-like protein 1; Nell1; neural epidermal growth factor-like 1; unnamed protein product
Gene Aliases: B230343H07Rik; IDH3GL; l7R6
UniProt ID: (Human) Q92832, (Mouse) Q2VWQ2, (Rat) Q62919
Entrez Gene ID: (Human) 4745, (Mouse) 338352, (Rat) 81733
regulation of gene expression
positive regulation of bone mineralization
negative regulation of osteoblast proliferation
negative regulation of protein catabolic process
positive regulation of apoptotic process
regulation of osteoblast differentiation
positive regulation of osteoblast differentiation
positive regulation of ossification
nervous system development
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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