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Invitrogen
PPP3CB Polyclonal Antibody
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FIGURE: 1 / 3
PPP3CB Antibody (PA5-100307) in ICC/IF
Immunofluorescent analysis of PPP3CB in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and PPP3CB polyclonal antibody (Product # PA5-100307) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100307
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PPP3CB, corresponding to a region within C-terminal amino acids.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PPP3CB.
Target Information
PPP3CB is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcineurin A beta; calcineurin A1; calcineurin A2; CAM-PRP catalytic subunit; CNA beta; PP2BA beta; protein phosphatase 3, catalytic subunit, beta isozyme; protein phosphatase from PCR fragment H32; RP11-345K20.1; unnamed protein product
Gene Aliases: 1110063J16Rik; CALNA2; CALNB; CNA2; Cnab; CnAbeta; PP2Bbeta
UniProt ID: (Human) P16298, (Mouse) P48453
Entrez Gene ID: (Human) 5532, (Mouse) 19056
protein serine/threonine phosphatase activity
calcium ion binding
protein binding
calmodulin binding
hydrolase activity
enzyme binding
protein phosphatase 2B binding
calmodulin-dependent protein phosphatase activity
protein dimerization activity
calcium-dependent protein serine/threonine phosphatase activity
macromolecular complex binding
negative regulation of T cell mediated cytotoxicity
lymphangiogenesis
protein phosphorylation
protein dephosphorylation
response to stress
lysosome organization
heart development
regulation of gene expression
calcium ion regulated exocytosis
negative regulation of signaling
T cell differentiation
locomotion involved in locomotory behavior
calcineurin-NFAT signaling cascade
response to cytokine
positive regulation of insulin secretion involved in cellular response to glucose stimulus
T cell homeostasis
negative regulation of innate immune response
positive regulation of transcription from RNA polymerase II promoter
skeletal muscle fiber development
regulation of insulin secretion
positive regulation of calcineurin-NFAT signaling cascade
calcineurin-mediated signaling
antibacterial innate immune response
negative regulation of protein localization to nucleus
positive regulation of protein localization to nucleus
regulation of synaptic vesicle endocytosis
positive regulation of calcium ion import across plasma membrane
positive regulation of lysosome organization
negative regulation of calcium ion import across plasma membrane
signal transduction
learning
memory
dephosphorylation
T cell proliferation
T cell activation
positive regulation of transcription, DNA-templated
regulation of synaptic plasticity
axon extension
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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