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Invitrogen
PLCB4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-100855
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PLCB4(Accession Q15147), corresponding to amino acid residues Q851-L901.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PLCB4.
Target Information
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This form has a role in retina signal transduction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; dJ1119D9.2 (Phopholipase C, beta 4 (1-Phosphatidylinositol-4,5-Bisphosphate Phosphodiesterase Beta 4)); inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-beta-4; phosphoinositide-specific phospholipase c; phospholipase C-beta 4b; PLC-beta-4; triphosphoinositide phosphodiesterase; unnamed protein product
Gene Aliases: A930039J07Rik; ARCND2; ARCND2A; ARCND2B; Beta4aa; C230058B11Rik; PI-PLC; RATBETA4AA
UniProt ID: (Human) Q15147, (Rat) Q9QW07
Entrez Gene ID: (Human) 5332, (Rat) 25031, (Mouse) 18798
lipid metabolic process
signal transduction
phototransduction
lipid catabolic process
intracellular signal transduction
negative regulation of potassium ion transport
phosphatidylinositol metabolic process
phosphatidylinositol-mediated signaling
modulation of synaptic transmission
release of sequestered calcium ion into cytosol
phospholipase C-activating endothelin receptor signaling pathway
G-protein coupled receptor signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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