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Invitrogen
RASAL2 Polyclonal Antibody
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FIGURE: 1 / 2
RASAL2 Antibody (PA5-100903) in IHC (P)
Immunohistochemistry analysis of RASAL2 in mouse heart tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with RASAL2 polyclonal antibody (Product # PA5-100903) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-100903
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RASAL2(Accession Q9UJF2), corresponding to amino acid residues S615-S665.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RASAL2.
Target Information
This gene encodes a protein that contains the GAP-related domain (GRD), a characteristic domain of GTPase-activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ras GTPase activating protein; Ras GTPase-activating protein nGAP; Ras protein activator like 1; RAS protein activator-like 2; RASAL2/ACVR1 fusion; unnamed protein product
Gene Aliases: 6530401P13; A330066M24Rik; NGAP; RASAL2
UniProt ID: (Human) Q9UJF2
Entrez Gene ID: (Human) 9462, (Mouse) 226525
response to dietary excess
signal transduction
response to glucose
gene expression
multicellular organism growth
adipose tissue development
regulation of intracellular signal transduction
regulation of protein activation cascade
positive regulation of GTPase activity
negative regulation of Ras protein signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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