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Invitrogen
Adenylate Cyclase 4 Polyclonal Antibody
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FIGURE: 1 / 4
Adenylate Cyclase 4 Antibody (PA5-101283) in ICC/IF
Immunofluorescent analysis of Adenylate Cyclase 4 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and Adenylate Cyclase 4 polyclonal antibody (Product # PA5-101283) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-101283
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human ADCY4(Accession Q8NFM4), corresponding to amino acid residues D863-L913.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total ADCY4.
Target Information
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: A cyclase IV; adenylate cyclase type IV; adenylyl cyclase 4; ATP pyrophosphate-lyase 4; KIAA4004; oxygen-phosphorus lyase; unnamed protein product
Gene Aliases: AC4; mKIAA4004
UniProt ID: (Human) Q8NFM4, (Mouse) Q91WF3
Entrez Gene ID: (Human) 196883, (Rat) 54223, (Mouse) 104110
cAMP biosynthetic process
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
cyclic nucleotide biosynthetic process
intracellular signal transduction
activation of adenylate cyclase activity
renal water homeostasis
cellular response to glucagon stimulus
vascular endothelial cell response to laminar fluid shear stress
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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