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PRPH2 Polyclonal Antibody
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FIGURE: 1 / 2
PRPH2 Antibody (PA5-106336) in ICC/IF
Immunofluorescent analysis of PRPH2 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and PRPH2 polyclonal antibody (Product # PA5-106336) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-106336
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PRPH2(Accession P23942), corresponding to amino acid residues P147-K197.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total PRPH2.
Target Information
Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: choroidal dystrophy, central areolar 2; peripherin 2 (retinal degeneration, slow); peripherin 2, homolog of mouse; peripherin, photoreceptor type; retinal degeneration 2; retinal degeneration slow protein; retinal degeneration, slow; retinal degeneration, slow (retinitis pigmentosa 7); retinal peripherin; tetraspanin-22; tspan-22; unnamed protein product
Gene Aliases: AOFMD; AVMD; CACD2; DS; MDBS1; Nmf193; PRPH; Rd-2; Rd2; RDS; RP7; RSRDS; TSPAN22
UniProt ID: (Human) P23942, (Mouse) P15499, (Rat) P17438
Entrez Gene ID: (Human) 5961, (Mouse) 19133, (Rat) 25534
visual perception
response to light stimulus
response to low light intensity stimulus
photoreceptor cell outer segment organization
detection of light stimulus involved in visual perception
protein homooligomerization
protein heterooligomerization
protein maturation
retina development in camera-type eye
protein localization to plasma membrane
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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