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Invitrogen
Rap1B Polyclonal Antibody
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Product Details
PA5-106370
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RAP1B(Accession P61224), corresponding to amino acid residues K149-L184.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total RAP1B.
Target Information
Ran (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The Ran protein is also involved in control of DNA synthesis and cell cycle progression. Nuclear localization of Ran requires the presence of regulator of chromosome condensation 1 (RCC1).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GTP-binding protein smg p21B; NB4 apoptosis/differentiation related protein; RAP1B; Ras family small GTP binding protein RAP1B; RAS related protein 1b; Ras-related protein Rap-1b; RAS-related protein RAP1B; small GTP binding protein; unnamed protein product
Gene Aliases: 2810443E11Rik; K-REV; OK/SW-cl.11; RAL1B; RAP1B; THC11
UniProt ID: (Human) P61224, (Rat) Q62636, (Mouse) Q99JI6
Entrez Gene ID: (Human) 5908, (Rat) 171337, (Mouse) 215449
signal transduction
small GTPase mediated signal transduction
cell proliferation
calcium ion regulated exocytosis
Rap protein signal transduction
positive regulation of integrin activation
negative regulation of calcium ion-dependent exocytosis
establishment of localization in cell
establishment of endothelial barrier
positive regulation of ERK1 and ERK2 cascade
cellular response to cAMP
modification of postsynaptic structure
regulation of cell junction assembly
regulation of establishment of cell polarity
negative regulation of synaptic vesicle exocytosis
metabolic process
microvillus assembly
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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