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CD94 Polyclonal Antibody
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FIGURE: 1 / 1
CD94 Antibody (PA5-109889) in WB
Western blot analysis of CD94 in extracts of various cell lines. Samples were incubated with CD94 Polyclonal antibody (Product # PA5-109889) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-109889
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 32-179 of human KLRD1 (NP_0022532)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.81 mg/mL
Amount
81 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KNSFTKLSIE PAFTPGPNIE LQKDSDCCSC QEKWVGYRCN CYFISSEQKT WNESRHLCAS QKSSLLQLQN TDELDFMSSS QQFYWIGLSY SEEHTAWLWE NGSALSQYLF PSFETFNTKN CIAYNPNGNA LDESCEDKNR YICKQQLI
Target Information
Natural killer (NK) cells, like CD94, are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-type lectin; CD94; CD94 antigen; CD94 antigen (located within the rat natural killer gene complex); killer cell lectin-like receptor subfamily D, member 1; killer cell lectin-like receptor, subfamily D, member 1; KLRD1; KP43; natural killer cell receptor; NK cell receptor; unnamed protein product
Gene Aliases: CD94
UniProt ID: (Human) Q13241, (Mouse) O54707, (Rat) O35778
Entrez Gene ID: (Human) 3824, (Mouse) 16643, (Rat) 25110
negative regulation of T cell mediated cytotoxicity
stimulatory C-type lectin receptor signaling pathway
natural killer cell mediated immunity
cell surface receptor signaling pathway
regulation of natural killer cell activation
negative regulation of natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
biological_process
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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