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Invitrogen
LGR4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-109908
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein (or fragment)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.84 mg/mL
Amount
184 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HLESLTLTGT KISSIPNNLC QEQKMLRTLD LSYNNIRDLP SFNGCHALEE ISLQRNQIYQ IKEGTFQGLI SLRILDLSRN LIHEIHSRAF ATLGPITNLD VSFNELTSFP TEGLNGLNQL KLVGNFKLKE ALAAKDFVNL RSLSVPYAYQ CCAFWGCDSY ANLNTEDNSL QDHSVAQEKG TADAANVTST LENEEHSQII IHCTPSTGAF KPCEYLLGSW M
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR LGR4 is a member of this family (subfamily Orphan-A). Its expression has been documented in human brain, adrenal, heart, kidney, liver, skeletal muscle, ovary, pancreas, placenta, prostate, spleen, stomach, testis, thyroid, and spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein-coupled receptor 48; G protein-coupled receptor GPR48; G-protein coupled receptor 48; leucine-rich repeat containing G protein-coupled receptor; leucine-rich repeat-containing G-protein coupled receptor 4; unnamed protein product
Gene Aliases: 9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; DPSL; GPR48
UniProt ID: (Human) Q9BXB1, (Rat) Q9Z2H4, (Mouse) A2ARI4
Entrez Gene ID: (Human) 55366, (Rat) 286994, (Mouse) 107515
osteoblast differentiation
negative regulation of cytokine production
hair follicle development
G-protein coupled receptor signaling pathway
spermatogenesis
axon guidance
circadian rhythm
biological_process
cell proliferation
bone mineralization
male genitalia development
circadian regulation of gene expression
negative regulation of toll-like receptor signaling pathway
tube morphogenesis
intestinal stem cell homeostasis
bone remodeling
digestive tract development
epithelial cell proliferation
negative chemotaxis
metanephric glomerulus development
metanephric nephron tubule morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of canonical Wnt signaling pathway
negative regulation of cold-induced thermogenesis
epithelial cell proliferation involved in renal tubule morphogenesis
positive regulation of Wnt signaling pathway
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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