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Invitrogen
Phospho-MPZL1 (Tyr263) Polyclonal Antibody
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FIGURE: 1 / 3
Phospho-MPZL1 (Tyr263) Antibody (PA5-114629) in IHC (P)
Immunohistochemistry analysis of Phospho-MPZL1 (Tyr263) in mouse lung tissue sections. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114629) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-114629
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MPZL1(Accession O95297), corresponding to amino acid residues around phosphorylated Tyr263.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of PZR only when phosphorylated at Tyr263.
Target Information
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ21047; immunoglobulin family transmembrane protein; immunoglobulin superfamily member; isoform 1; isoform 2; isoform 3; MPZL1; protein zero related; protein zero-related; transmembrane protein; mPZR; transmembrane protein; mPZRb; PZRb; unnamed protein product
Gene Aliases: 1110007A10Rik; MPZL1b; PZR; PZR1b; PZRa; PZRb
UniProt ID: (Human) O95297, (Rat) Q6AYT8, (Mouse) Q3TEW6
Entrez Gene ID: (Human) 9019, (Rat) 360871, (Mouse) 68481
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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