Search
Invitrogen
Chordin Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 5
Chordin Antibody (PA5-115015) in IHC (P)
Immunohistochemistry analysis of Chordin in mouse kidney tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115015) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115015
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human CHRD(Accession Q9H2X0), corresponding to amino acid residues T124-A174.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total Chordin.
Target Information
This gene encodes a secreted protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta-like bone morphogenetic proteins and sequestering them in latent complexes. The encoded protein may also have roles in organogenesis and during adulthood. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Chd; secreted protein; putative secreted antagonist of transforming growth factor beta-like morphogens; unnamed protein product
Gene Aliases: Chd
UniProt ID: (Human) Q9H2X0, (Mouse) Q9Z0E2
Entrez Gene ID: (Human) 8646, (Rat) 117275, (Mouse) 12667
embryonic axis specification
skeletal system development
osteoblast differentiation
in utero embryonic development
gastrulation with mouth forming second
mesoderm formation
positive regulation of mesenchymal cell proliferation
smoothened signaling pathway
pattern specification process
central nervous system development
cell proliferation
visual learning
fibroblast growth factor receptor signaling pathway
dorsal/ventral pattern formation
gene expression
neural crest formation
mesenchymal cell fate commitment
protein import
spinal cord dorsal/ventral patterning
negative regulation of cell migration
BMP signaling pathway
negative regulation of BMP signaling pathway
forebrain development
embryonic heart tube development
exploration behavior
descending aorta development
maintenance of protein location
negative regulation of osteoblast differentiation
positive regulation of cell adhesion
regulation of neuronal synaptic plasticity
neuron fate commitment
system development
artery morphogenesis
venous blood vessel morphogenesis
synapse organization
long-term synaptic potentiation
epithelial cell fate commitment
presynaptic modulation of chemical synaptic transmission
chordate pharynx development
cranial skeletal system development
short-term synaptic potentiation
floor plate development
specification of segmental identity, mandibular segment
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support