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Invitrogen
DNAH1 Polyclonal Antibody
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FIGURE: 1 / 3
DNAH1 Antibody (PA5-115132) in ICC/IF
Immunocytochemistry analysis of DNAH1 in HeLa cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115132) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied with mouse anti-beta tubulin; AlexaFluor 594 conjugated goat anti-rabbit IgG (Red); AlexaFluor 88 conjugated goat anti-mouse IgG (Green) and DAPI (blue) using a dilution of 1:200 (1 hr at 37°C).
Product Details
PA5-115132
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human DNAH1(Accession Q9P2D7), corresponding to amino acid residues T3124-Q3174.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total DNAH1.
Target Information
This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Dynein axonemal heavy chain 1; dynein heavy chain 1, axonemal; dynein, axonemal, heavy polypeptide 1; hDHC7; Heat shock regulated protein 1; HSRF-1; testicular tissue protein Li 60; unnamed protein product; XLHSRF-1
Gene Aliases: CILD37; DHC7; Dlp1; DNAH1; DNAHC1; HDHC7; HL-11; HL11; HSRF-1; KIAA1410; RGD1311110; SPGF18; XLHSRF-1
UniProt ID: (Human) Q9P2D7, (Rat) Q63164
Entrez Gene ID: (Human) 25981, (Rat) 171339
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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