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Invitrogen
Axotrophin Polyclonal Antibody
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FIGURE: 1 / 3
Axotrophin Antibody (PA5-115545) in ICC/IF
Immunocytochemistry analysis of Axotrophin in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with Axotrophin polyclonal antibody (Product # PA5-115545) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-115545
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MARCH7(Accession Q9H992), corresponding to amino acid residues Y67-S117.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MARCH7.
Target Information
The function of protein remains unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: axotrophin; C3HC4 7; DKFZP586F1122; E3 ubiquitin-protein ligase MARCH7; membrane associated ring finger 7; membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase; membrane-associated RING finger protein 7; membrane-associated RING-CH protein VII; RING finger protein 177; RING-type E3 ubiquitin transferase MARCH7; RING-type E3 ubiquitin transferase MARCHF7; unnamed protein product
Gene Aliases: AXO; AXOT; MARCH-VII; MARCH7; RNF177
UniProt ID: (Human) Q9H992
Entrez Gene ID: (Human) 64844
protein monoubiquitination
positive regulation of cell proliferation
protein ubiquitination
negative regulation of DNA damage response, signal transduction by p53 class mediator
protein stabilization
protein autoubiquitination
negative regulation of proteasomal protein catabolic process
negative regulation of cilium assembly
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of protein polyubiquitination
negative regulation of protein autoubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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