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Invitrogen
TIPARP Polyclonal Antibody
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FIGURE: 1 / 2
TIPARP Antibody (PA5-116171) in WB
Western Blot analysis of TIPARP using the TIPARP Polyclonal Antibody (Product # PA5-116171) at a 1:500 dilution. mouse kidney lysates were loaded at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size: 76 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-116171
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human Tiparp
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
2 mg/mL
Amount
800 µg
Purification
Ammonium sulfate precipitation
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
TIPARP is a poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. TIPARP may play a role in the adaptative response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP-ribosyltransferase diphtheria toxin-like 14; DDF1; DKFZP434J214; DKFZp686N0351; DKFZp686P1838; FLJ40466; PARP-1; poly [ADP-ribose] polymerase 7; unnamed protein product
Gene Aliases: ARTD14; PARP7; pART14
UniProt ID: (Human) Q7Z3E1, (Mouse) Q8C1B2
Entrez Gene ID: (Human) 25976, (Mouse) 99929
core promoter proximal region sequence-specific DNA binding
NAD+ ADP-ribosyltransferase activity
metal ion binding
NAD+-protein-cysteine ADP-ribosyltransferase activity
NAD+-protein-aspartate ADP-ribosyltransferase activity
NAD+-protein-glutamate ADP-ribosyltransferase activity
protein ADP-ribosylase activity
negative regulation of gene expression
positive regulation of protein catabolic process
protein auto-ADP-ribosylation
response to 2,3,7,8-tetrachlorodibenzodioxine
vasculogenesis
kidney development
androgen metabolic process
estrogen metabolic process
female gonad development
post-embryonic development
hemopoiesis
platelet-derived growth factor receptor signaling pathway
skeletal system morphogenesis
smooth muscle tissue development
palate development
face morphogenesis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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