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Phospho-RGS19 (Ser151) Polyclonal Antibody
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Phospho-RGS19 (Ser151) Antibody (PA5-118694) in IHC (P)
Immunohistochemical analysis of Phospho-RGS19 (Ser151) in Mouse brain tissue using a Phospho-RGS19 (Ser151) polyclonal antibody (Product # PA5-118694). The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4°C overnight. An HRP conjugated anti-Rabbit antibody was used as the seconda... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-118694
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RGS19(Accession P49795), corresponding to amino acid residues around phosphorylated Ser151.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
sequential chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of RGS19 only when phosphorylated at Ser151.
Target Information
RGS19 inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, predominantly to G(i)-alpha-3. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: calcium/calmodulin-dependent protein kinase I; G alpha interacting protein; G protein signalling regulator 19; G-alpha interacting protein; GAIP; GAIP protein; GS19; guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; regulator of G protein signaling; regulator of G-protein signaling 19; regulator of G-protein signalling 19; RGS protein; RGS19; unnamed protein product
Gene Aliases: 2610042F04Rik; Camki; GAIP; RGSGAIP
UniProt ID: (Human) P49795, (Mouse) Q9CX84, (Rat) O70521
Entrez Gene ID: (Human) 10287, (Mouse) 56470, (Rat) 59293
G-protein coupled receptor signaling pathway
negative regulation of G-protein coupled receptor protein signaling pathway
small GTPase mediated signal transduction
protein targeting
chemical synaptic transmission
regulation of G-protein coupled receptor protein signaling pathway
glutamate secretion
positive regulation of transforming growth factor beta receptor signaling pathway
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
endothelial cell migration
response to ethanol
regulation of synaptic plasticity
cellular response to interleukin-7
presynaptic modulation of chemical synaptic transmission
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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