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Invitrogen
FLT3LG Polyclonal Antibody
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FIGURE: 1 / 5
FLT3LG Antibody (PA5-119123) in IHC (P)
Immunohistochemistry (Paraffin) analysis of FLT3LG in mouse cerebrum tissue using FLT3LG Polyclonal Antibody (Product # PA5-119123) (10μg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Rabbit IgG polyclonal secondary antibody (2 µg/mL). DAB staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-119123
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein FMS Like Tyrosine Kinase 3 Ligand. The antigen corresponds to amino acid range 27-189 of the target protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
FLT3LG (Fms Related Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Brain Cancer. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cytokine; Flt 3 ligand; Flt3 L; flt3 ligand; H-FLT-3-L; hematopoietic growth factor; M-FLT-3-L; unnamed protein product
Gene Aliases: Flt3lg; Ly72L
UniProt ID: (Mouse) P49772
Entrez Gene ID: (Mouse) 14256
natural killer cell differentiation
positive regulation of protein phosphorylation
signal transduction
positive regulation of cell proliferation
lymphocyte differentiation
B cell differentiation
regulation of myeloid dendritic cell activation
positive regulation of natural killer cell differentiation
embryonic hemopoiesis
positive regulation of myoblast differentiation
positive regulation of cell cycle
positive regulation of transcription from RNA polymerase II promoter
homeostasis of number of cells within a tissue
positive regulation of cell proliferation in bone marrow
negative regulation of apoptotic process in bone marrow
positive regulation of osteoclast proliferation
dendritic cell differentiation
positive regulation of myoblast fusion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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