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HPa1 Polyclonal Antibody
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FIGURE: 1 / 8
HPa1 Antibody (PA5-119186) in ICC/IF
Immunocytochemistry analysis of HPa1 in Human HepG2 cells using HPa1 Polyclonal Antibody (Product # PA5-119186) at a dilution of 20 µg/mL, followed by secondary antibody staining with 1.5 µg/mL FITC-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-119186
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein Heparanase. The antigen corresponds to amino acid range 34-115 of the target protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al. ). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: endo-beta-D-glucuronidase; endo-glucoronidase; endoglycosidase; heparanase-1; unnamed protein product
Gene Aliases: HPA; HPA1; HPR1; HPSE1; HSE1
UniProt ID: (Human) Q9Y251
Entrez Gene ID: (Human) 10855
positive regulation of cell-matrix adhesion
Factor XII activation
proteoglycan metabolic process
inflammatory response
cell-matrix adhesion
positive regulation of cell proliferation
positive regulation of autophagy
positive regulation of vascular endothelial growth factor production
positive regulation of blood coagulation
heparan sulfate proteoglycan catabolic process
heparin metabolic process
positive regulation of cell migration
positive regulation of osteoblast proliferation
wound healing
positive regulation of angiogenesis
response to antibiotic
regulation of hair follicle development
positive regulation of hair follicle development
positive regulation of protein kinase B signaling
angiogenesis involved in wound healing
establishment of endothelial barrier
vascular wound healing
protein transmembrane transport
positive regulation of extracellular matrix disassembly
positive regulation of substrate adhesion-dependent cell spreading
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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