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Invitrogen
FOXM1 Polyclonal Antibody
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FIGURE: 1 / 4
FOXM1 Antibody (PA5-119635) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of FOXM1 in HUVEC cells (green) using FOXM1 Polyclonal Antibody (Product # PA5-119635). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Product Details
PA5-119635
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein within human FOXM1 aa 102-340.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: A549, HUVEC, LOVO.
Subcellular Location: Nucleus.
Target Information
FOXM1 (forkhead box protein M1) is a transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. FOXM1 plays a role in the control of cell proliferation and DNA break repairs participating in the DNA damage checkpoint response.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cell proliferation-inducing gene 29 protein; FKH L16; FKHL 16; forkhead box M1-D; Forkhead box protein M1; forkhead homolog 16; Forkhead like 16; Forkhead, drosophila, homolog-like 16; Forkhead-related protein FKHL16; FOXM 1; FOXM 1c; Hepatocyte nuclear factor 3 forkhead homolog 11; hepatocyte nuclear factor-3/fork head homolog 11A; winged helix transcription factor; HFH 11; HFH-11; HNF 3; HNF-3/fork-head homolog 11; HNF3; INS 1; INS1; M-phase phosphoprotein 2; MPHOSPH 2; MPM 2; MPM-2 reactive phosphoprotein 2; MPP 2; PIG 29; TGT3; Transcription factor Trident; trident; unnamed protein product; winged helix transcription factor; hepatocyte nuclear factor-3/fork head homolog 11B; Winged-helix factor from INS-1 cells; winged-helix transcription factor Trident
Gene Aliases: AA408308; AW554517; BB238854; Fkh16; FKHL16; FOXM1; FOXM1A; FOXM1B; FOXM1C; HFH-11; HFH-11B; HFH11; HNF-3; INS-1; MPHOSPH2; Mpm2; MPP-2; MPP2; PIG29; TRIDENT; WIN
UniProt ID: (Human) Q08050
Entrez Gene ID: (Human) 2305, (Mouse) 14235
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein kinase binding
sequence-specific DNA binding
transcription regulatory region DNA binding
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
vasculogenesis
liver development
DNA repair
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
cell cycle
positive regulation of cell proliferation
anatomical structure morphogenesis
negative regulation of stress-activated MAPK cascade
regulation of cell proliferation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of Ras protein signal transduction
regulation of cell cycle arrest
negative regulation of cell aging
regulation of reactive oxygen species metabolic process
positive regulation of double-strand break repair
regulation of mitotic cell cycle
DNA damage response, signal transduction by p53 class mediator
regulation of cell cycle
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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