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Invitrogen
GRP Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-120998
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-148 of human Gastrin Releasing Peptide (GRP) (NP_0020822)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: A-549, NCI-H460, Mouse lung, Mouse brain, Mouse stomach, Rat lung, Rat brain, Rat stomach. The target is usually found in the following locations: Secreted.
Immunogen sequence: MRGRELPLVL LALVLCLAPR GRAVPLPAGG GTVLTKMYPR GNHWAVGHLM GKKSTGESSS VSERGSLKQQ LREYIRWEEA ARNLLGLIEA KENRNHQPPQ PKALGNQQPS WDSEDSSNFK DVGSKGKVGR LSAPGSQREG RNPQLNQQ
Target Information
GRP stimulates gastrin release as well as other gastrointestinal hormones. Operates as a negative feedback regulating fear and established a causal relationship between GRP-receptor gene expression, long-term potentiation, and amygdala-dependent memory for fear.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bombesin; neuromedin C; pre-progastrin releasing peptide; prepro-GRP; preprogastrin-releasing peptide; testicular tissue protein Li 103; unnamed protein product
Gene Aliases: BLP; BN; GRP-10; preproGRP; proGRP
UniProt ID: (Human) P07492, (Mouse) Q8R1I2, (Rat) P24393
Entrez Gene ID: (Human) 2922, (Mouse) 225642, (Rat) 171101
ossification
neuropeptide signaling pathway
regulation of gene expression
social behavior
psychomotor behavior
response to external biotic stimulus
mast cell degranulation
negative regulation of transmission of nerve impulse
positive regulation of peptide hormone secretion
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of respiratory gaseous exchange
positive regulation of vascular associated smooth muscle cell apoptotic process
positive regulation of behavioral fear response
signal transduction
cellular response to sodium phosphate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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