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ARL6IP6 Polyclonal Antibody
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FIGURE: 1 / 12
ARL6IP6 Antibody (PA5-144044) in ICC/IF
Immunocytochemistry analysis of ARL6IP6 in Caco-2 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in ARL6IP6 Polyclonal antibody (Product # PA5-144044) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Rabbit IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropr... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-144044
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human ARL6IP6 (VARDLRAEFSAGA) (aa 51-63).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human 293T whole cell, human Caco-2 whole cell, rat lung tissue, mouse testis tissue, mouse lung tissue. IHC: human bladder epithelial carcinoma tissue, human bladder epithelial carcinoma tissue, human gastric cancer tissue, human lung cancer tissue, human ovarian cancer tissue, human metaplasia of squamous cells of the renal pelvis tissue. ICC/IF: Caco-2 cell. Flow: HEPA1-6 cell, HL-60 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
The ARL6IP6 gene has been identified as a novel candidate gene associated with a syndromic form of Cutis Marmorata Telangiectatica Congenita (CMTC), suggesting that ischemic stroke or transient ischemic attacks (TIA) might represent the mild end of the phenotypic spectrum, with autosomal recessive CMTC as the severe manifestation. The ARL6IP6 influences the susceptibility to these conditions, highlighting its importance in vascular and dermatological syndromes. Mutations in ARL6IP6 can lead to a range of phenotypic outcomes, from mild ischemic events to serious congenital skin disorders, emphasizing the need for deeper genetic and phenotypic exploration to understand its role in human pathology. Moreover, the gene is potentially involved in intracellular trafficking processes that are crucial for proper cellular function, which can be impacted by genetic variations, leading to clinical manifestations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ADP ribosylation factor like GTPase 6 interacting protein 6; ADP-ribosylation factor GTPase 6 interacting protein 6; ADP-ribosylation factor-like 6 interacting protein 6; ADP-ribosylation-like factor 6 interacting protein 6; ADP-ribosylation-like factor 6-interacting protein 6; aip-6; ARL-6-interacting protein 6; phosphonoformate immuno-associated protein 1; regulated by phosphonoformate; unnamed protein product
Gene Aliases: 2310057C01Rik; 2610529A11Rik; AIP-6; AIP6; PFAAP1
UniProt ID: (Human) Q8N6S5, (Mouse) Q8BH07, (Rat) Q68FV2
Entrez Gene ID: (Human) 151188, (Mouse) 65103, (Rat) 499798
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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