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Invitrogen
PRPF4B Polyclonal Antibody
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FIGURE: 1 / 2
PRPF4B Antibody (PA5-14485) in IHC (P)
Immunohistochemistry analysis of PRPF4B in formalin-fixed and paraffin-embedded human cancer tissue. Samples were incubated with PRPF4B polyclonal antibody (Product # PA5-14485) which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = he... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-14485
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 948-978 amino acids from the C-terminal region of human PRP4
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
Target Information
Pre-mRNA splicing occurs in two sequential transesterification steps, and the protein encoded by this gene is thought to be involved in pre-mRNA splicing and in signal transduction. This protein belongs to a kinase family that includes serine/arginine-rich protein-specific kinases and cyclin-dependent kinases. This protein is regarded as a CDK-like kinase with homology to mitogen-activated protein kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dJ1013A10.1 (PRP4 protein kinase homolog); hPRP4K; SR protein kinase; pre-mRNA processing factor 4B; protein-serine/threonine kinase; PRP4 kinase; PRP4 pre-mRNA processing factor 4 homolog B; PRP4 pre-mRNA-processing factor 4 homolog; RP5-1013A10.2; unnamed protein product
Gene Aliases: dJ1013A10.1; PR4H; PRP4; Prp4B; PRP4H; PRPF4B
UniProt ID: (Human) Q13523
Entrez Gene ID: (Human) 8899
spliceosomal tri-snRNP complex assembly
spliceosomal snRNP assembly
spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
mRNA splicing, via spliceosome
positive regulation of hippo signaling
mRNA cis splicing, via spliceosome
positive regulation of protein export from nucleus
regulation of mitotic cell cycle spindle assembly checkpoint
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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