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Invitrogen
NAMPT Polyclonal Antibody
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FIGURE: 1 / 8
NAMPT Antibody (PA5-145297) in IHC (P)
Immunohistochemistry (Paraffin) analysis of NAMPT in Human Stomach Tissue. Samples were incubated in NAMPT polyclonal antibody (Product # PA5-145297) using a dilution of 20 µg/mL followed by HRP-Linked Caprine Anti-Rabbit IgG at a dilution of 2 µg/mL and DAB staining.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-145297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human VF protein, Met1-His491 (Accession #P43490)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% Proclin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Visfatin, also known as pre-B cell colony-enhancing factor, is an adipocytokine that is abundantly secreted by visceral adipose tissue, with insulin mimetic effects. Visfatin mimics insulin signaling by binding to the insulin receptor and reducing glucose release from liver cells, while stimulating glucose utilization in adipocytes and myocytes. Visfatin is also invoved in enhancement of cell proliferation, biosynthesis of nicotinamide mono-and dinucleotide and glucose homeostasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp666B131; EC 2.4.2.12; MGC117256; NAmPRTase; NAMPT; PBEF; PBEF1; visfatin; pre-B cell-enhancing factor; pre-B-cell colony enhancing factor 1; pre-B-cell colony-enhancing factor 1; pre-B-cell colony-enhancing factor 1 homolog; putative cytokine; unnamed protein product; visfatin
Gene Aliases: 1110035O14Rik; NAmPRTase; PBEF; PBEF1; VF; VISFATIN
UniProt ID: (Pig) Q52I78, (Human) P43490, (Mouse) Q99KQ4, (Rat) Q80Z29
Entrez Gene ID: (Pig) 595123, (Human) 10135, (Mouse) 59027, (Rat) 297508
signal transduction
NAD biosynthetic process
circadian regulation of gene expression
positive regulation of transcription from RNA polymerase II promoter
positive regulation of nitric-oxide synthase biosynthetic process
NADP biosynthetic process
inflammatory response
cell-cell signaling
circadian rhythm
positive regulation of cell proliferation
insulin receptor signaling pathway
positive regulation of gene expression
NAD salvage
positive regulation of I-kappaB kinase/NF-kappaB signaling
adipose tissue development
positive regulation of ERK1 and ERK2 cascade
nicotinate metabolic process
microglial cell activation
negative regulation of autophagy
regulation of lung blood pressure
positive regulation of smooth muscle cell proliferation
negative regulation of cellular senescence
female pregnancy
cellular response to hypoxia
cellular response to ionizing radiation
cellular response to beta-amyloid
response to D-galactose
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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