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Antibody Testing Data (9)

S100B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 9

S100B Antibody (PA5-145375) in IHC (P)

Immunohistochemistry (Paraffin) analysis of S100B in rat spinal cord tissue using S100B Polyclonal Antibody (Product # PA5-145375) (10 µg/mL) and using PBS intead of the primary antibody as a control. The sample was then stained with HRP-Goat anti-Rabbit IgG polyclonal secondary antibody (2 µg/mL). DAB staining.

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image S100B Polyclonal Antibody

Product Details

PA5-145375

Applications

Tested Dilution

Publications

Western Blot (WB)

0.01-2 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

5-20 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Pig, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human S100B protein, Met1-Glu92 (Accession #P04271)

3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

100 µg

Purification

Antigen affinity chromatography, Protein A

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.05% Proclin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Ambient (domestic); Wet ice (international)

AB_3094072

Target Information

S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: S-100 calcium-binding protein, beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein, beta (neural); S100 protein beta chain; S100 protein, beta polypeptide, neural; S100B; unnamed protein product

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Gene Aliases: Bpb; NEF; S100; S100-B; S100beta; S100P

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UniProt ID: (Human) P04271, (Rat) P04631, (Mouse) P50114

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Entrez Gene ID: (Human) 6285, (Pig) 100623510, (Rat) 25742, (Mouse) 20203

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Function(s)

receptor binding calcium ion binding protein binding zinc ion binding identical protein binding protein homodimerization activity S100 protein binding tau protein binding calcium-dependent protein binding RAGE receptor binding calmodulin-related

Process(es)

axonogenesis central nervous system development learning or memory positive regulation of cell proliferation regulation of cell shape positive regulation of myelination positive regulation of apoptotic process positive regulation of I-kappaB kinase/NF-kappaB signaling response to ethanol positive regulation of neuron differentiation astrocyte differentiation positive regulation of synaptic transmission response to glucocorticoid response to methylmercury long-term synaptic potentiation cellular response to hypoxia response to anesthetic sympathetic neuron projection extension neuron projection extension adaptive thermogenesis negative regulation of skeletal muscle cell differentiation memory regulation of neuronal synaptic plasticity regulation of cytokine production energy reserve metabolic process cellular calcium ion homeostasis regulation of long-term neuronal synaptic plasticity

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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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S100B Polyclonal Antibody

S100B Antibody (PA5-145375) in IHC (P)

Product Details

PA5-145375

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Species Reactivity

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Amount

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Target Information

References (0)

Bioinformatics

Performance Guarantee

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