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Invitrogen
MAGED1 Polyclonal Antibody
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Product Details
PA5-148762
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human NRAGE, Arg73-Asn254
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 11B6; BCG-1; Dlxin-1; JCL-1; MAGE family member; MAGE tumor antigen CCF; MAGE-D1 antigen; Maged2; melanoma antigen family D, 1; melanoma antigen family D1; Melanoma-associated antigen D1; Neurotrophin receptor-interacting MAGE homolog; Sertoli cell necdin-related gene protein 1; SNERG-1; unnamed protein product
Gene Aliases: 2810433C11Rik; 5430405L04Rik; Dlixin; DLXIN-1; Dlxin1; DXBwg1492e; MAGE-D1; MAGED1; mFLJ00163; NRAGE; PP2250; PRO2292
UniProt ID: (Human) Q9Y5V3, (Mouse) Q9QYH6, (Rat) Q9ES73
Entrez Gene ID: (Human) 9500, (Mouse) 94275, (Rat) 84469
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
circadian regulation of gene expression
protein localization to nucleus
regulation of circadian rhythm
regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
rhythmic process
negative regulation of epithelial cell proliferation
positive regulation of branching involved in ureteric bud morphogenesis
negative regulation of protein localization to nucleus
positive regulation of apoptotic signaling pathway
positive regulation of MAP kinase activity
JUN phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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