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Invitrogen
BOK Polyclonal Antibody
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Product Details
PA5-149129
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human BOK, Met15-Val123
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains all four BCL-2 like domains and is a pro-apoptotic BCL-2 protein identified in the ovary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Apoptosis activator Mtd; Bcl-2-like protein 9; Bcl-2-related ovarian killer protein; BCL2 family apoptosis regulator; BCL2 related ovarian killer; Bcl2-L-9; BCL2-related ovarian killer protein; BOK, BCL2 family apoptosis regulator; hBOK; Protein matador
Gene Aliases: AI847676; AU021146; BCL2L9; BOK; Bok-BH3; BOKL; matador; Mtd
UniProt ID: (Human) Q9UMX3, (Rat) Q792S6, (Mouse) O35425
Entrez Gene ID: (Human) 666, (Rat) 29884, (Mouse) 51800
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
brain development
cell proliferation
male gonad development
intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of apoptotic process
oligodendrocyte differentiation
neuron apoptotic process
intrinsic apoptotic signaling pathway by p53 class mediator
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of execution phase of apoptosis
release of cytochrome c from mitochondria
cellular component disassembly involved in execution phase of apoptosis
regulation of autophagy
regulation of apoptotic process
negative regulation of neuron apoptotic process
protein oligomerization
regulation of cytosolic calcium ion concentration
negative regulation of mitochondrial depolarization
transmembrane transport
negative regulation of necroptotic process
response to cisplatin
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of chorionic trophoblast cell proliferation
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of PERK-mediated unfolded protein response
regulation of granulosa cell apoptotic process
positive regulation of intrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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