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Invitrogen
NME2 Polyclonal Antibody
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Product Details
PA5-149233
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human NM23-H2, Ala2-Glu152
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Nucleoside diphosphate kinase B is an enzyme that in humans is encoded by the NME2 gene. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) which encode a fusion protein consisting of sequence sharing identity with each individual gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2.7.13.3; C-myc purine-binding transcription factor PUF; c-myc transcription factor; epididymis secretory sperm binding protein Li 155an; HEL-S-155an; Histidine protein kinase NDKB; NDK2; NDP kinase B; nm23-H2; nm23-H2S product (putative NDP kinase); putative; NME2; non-metastatic cells 2, protein (NM23) expressed in; non-metastatic cells 2, protein (NM23B) expressed in; Nucleoside diphoshate kinase 2; Nucleoside diphosphate kinase B; nucleotide diphosphate kinase B
Gene Aliases: NDK2; NDKB; NDPK-B; NDPKB; NM23-H2; NM23B; NME2; PUF
UniProt ID: (Human) P22392
Entrez Gene ID: (Human) 4831
nucleotide binding
bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DNA binding
nuclease activity
nucleoside diphosphate kinase activity
protein histidine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
GDP binding
identical protein binding
metal ion binding
G-quadruplex DNA binding
GTP biosynthetic process
UTP biosynthetic process
CTP biosynthetic process
cell adhesion
integrin-mediated signaling pathway
nucleotide metabolic process
nucleoside triphosphate biosynthetic process
regulation of apoptotic process
negative regulation of apoptotic process
positive regulation of keratinocyte differentiation
regulation of epidermis development
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
ITP biosynthetic process
positive regulation of epithelial cell proliferation
positive regulation of DNA-templated transcription, initiation
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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