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Invitrogen
Viral MIP-III Polyclonal Antibody
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Product Details
PA5-149279
Product Specifications
Species Reactivity
Virus
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant human herpes virus-8 MIP-III, Ser27-Pro114
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
MIP-III, also known as CCL28 (C-C motif chemokine ligand 28), is a chemokine gene that plays a significant role in the immune system by directing the migration of immune cells to sites of inflammation and infection. The protein encoded by MIP-III is a member of the CC chemokine family and is primarily expressed in mucosal tissues such as the intestines, lungs, and mammary glands. MIP-III is known to attract a variety of immune cells, including T cells, B cells, and eosinophils, by binding to its receptors CCR3 and CCR10. This chemokine is involved in the mucosal immune response, helping to maintain immune surveillance and protect against pathogens. Additionally, MIP-III has been implicated in the pathogenesis of inflammatory diseases and allergic reactions due to its role in recruiting immune cells to affected tissues. Understanding the function and regulation of MIP-III is important for developing therapeutic strategies aimed at modulating immune cell trafficking in conditions such as inflammatory bowel disease, asthma, and other mucosal inflammatory disorders. Research into MIP-III also provides insights into the mechanisms of immune cell migration and the potential for targeting chemokines in immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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