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Invitrogen
Cdc42 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5150246
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Cell Division Cycle Protein 42 (CDC42) (Met1-Cys188)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Rac1 is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for the Rac1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cdc42; CDC42Mm; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; dJ224A6.1.1 (cell division cycle 42 (GTP-binding protein, 25kD)); dJ224A6.1.2 (cell division cycle 42 (GTP-binding protein, 25kD)); G25K GTP-binding protein; growth-regulating protein; GTP binding protein, 25kDa; GTP-binding protein; GTP-binding protein G25K; RP1-224A6.5; small GTP binding protein; small GTP binding protein CDC42; small GTP binding protein; GTPase; unnamed protein product
Gene Aliases: CDC42Hs; G25K; TKS
UniProt ID: (Human) P60953, (Mouse) P60766, (Rat) Q8CFN2
Entrez Gene ID: (Human) 998, (Mouse) 12540, (Rat) 64465
GTPase activity
obsolete small monomeric GTPase activity
protein binding
GTP binding
protein kinase binding
GTP-dependent protein binding
thioesterase binding
GBD domain binding
apolipoprotein A-I receptor binding
identical protein binding
ubiquitin protein ligase activity
mitogen-activated protein kinase kinase kinase binding
heart process
cardiac neural crest cell migration involved in outflow tract morphogenesis
endocytosis
phagocytosis, engulfment
actin filament organization
Golgi organization
establishment or maintenance of cell polarity
signal transduction
integrin-mediated signaling pathway
small GTPase mediated signal transduction
anatomical structure morphogenesis
regulation of lamellipodium assembly
positive regulation of lamellipodium assembly
substantia nigra development
establishment of cell polarity
actin cytoskeleton organization
macrophage differentiation
positive regulation of cell growth
positive regulation of cell migration
positive regulation of pseudopodium assembly
negative regulation of protein complex assembly
positive regulation of cytokinesis
regulation of actin cytoskeleton organization
cell junction assembly
embryonic heart tube development
neuropilin signaling pathway
modulation by host of viral process
establishment of epithelial cell apical/basal polarity
positive regulation of pinocytosis
positive regulation of cellular component organization
regulation of filopodium assembly
positive regulation of filopodium assembly
regulation of stress fiber assembly
positive regulation of stress fiber assembly
establishment of Golgi localization
regulation of attachment of spindle microtubules to kinetochore
Wnt signaling pathway, planar cell polarity pathway
positive regulation of epithelial cell proliferation involved in lung morphogenesis
dendritic spine morphogenesis
organelle transport along microtubule
endothelin receptor signaling pathway
regulation of postsynapse organization
positive regulation of substrate adhesion-dependent cell spreading
sprouting angiogenesis
cardiac conduction system development
protein phosphorylation
regulation of mitotic nuclear division
nuclear migration
Rho protein signal transduction
protein localization
endosomal transport
adherens junction organization
establishment or maintenance of apical/basal cell polarity
dendritic cell migration
positive regulation of catalytic activity
positive regulation of MAPK cascade
positive regulation of neuron apoptotic process
positive regulation of DNA replication
positive regulation of JNK cascade
filopodium assembly
neuron fate determination
nucleus localization
positive regulation of synapse structural plasticity
positive regulation of protein kinase B signaling
heart contraction
cellular response to interferon-gamma
actin filament branching
positive regulation of intracellular protein transport
cell-cell adhesion
regulation of modification of postsynaptic structure
response to glucose
regulation of exocytosis
submandibular salivary gland formation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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