Search
Invitrogen
H2AK5ac Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
{{$ctrl.translations['antibody.pdp.skuNotes.additionalInformation']}}:
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-17763
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic acetylated peptide corresponding to residues surrounding Lys5 of human histone H2A
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with other acetylated histones.
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Acetyl-Histone H2; Acetyl-Histone H2A K5; Acetyl-Histone H2A Lys5; H2A 615; H2A GL101; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member R; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A/d; H2a/x; h2ad; H2ae; H2AFX; H2AFZ; h2ai; H2ak; H2AK5ac; H2ALys5ac; H2AX histone; H2AZ histone; H2B histone family, member U, (testis-specific); HIS; HIST1H3D; HIST3H2A; histone (H2A.Z); histone 1, H2aa; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ah; histone 1, H2ai; histone 1, H2aj; histone 1, H2ba; histone 2, H2ai; histone 5 protein 2ax; histone cluster 1 H2A family member a; histone cluster 1 H2A family member b; histone cluster 1 H2A family member d; histone cluster 1 H2A family member e; histone cluster 1 H2A family member g; histone cluster 1 H2A family member h; histone cluster 1 H2A family member i; histone cluster 1 H2A family member j; histone cluster 1 H2B family member a; histone cluster 1, H2aa; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2ba; histone H2A type 1; Histone H2A type 1-B; Histone H2A type 1-E; Histone H2A type 1-G; histone H2A type 1-H; Histone H2A type 1-I; histone H2A, testis; histone H2A.3; histone H2A.x; histone H2A/a; histone H2A/g; histone H2A/m; histone H2A/p; histone H2A/ptl; histone H2A/r; histone H2A/s; histone H2AD; histone H2AE; histone H2B, testis; MGC74460; testis-specific histone 2a; testis-specific histone 2b; testis-specific histone H2B; unnamed protein product
Gene Aliases: 1190022L06; bA317E16.2; bA317E16.3; dJ160A22.4; dJ86C11.1; gammaH2ax; H2a-291A; H2a-53; H2A.1; H2A.1b; H2A.2; H2A.3; H2A.X; H2A.Z; H2A.Z-1; H2A.Z1; H2A/a; H2A/c; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2A/X; H2A/z; H2AA; H2AFA; H2AFALii; H2AFC; H2AFE; H2AFG; H2AFM; H2AFP; H2AFR; H2AFX; H2AFZ; H2AG; H2AH; H2AZ; H2BFU; HIST1H2AA; HIST1H2AB; HIST1H2AD; HIST1H2AE; HIST1H2AG; HIST1H2AH; HIST1H2AI; HIST1H2AJ; HIST1H2BA; Hist5-2ax; HISTH2AA; histone; hTSH2B; pH2A/f; RGD1566119; STBP; TH2A; TH2B; TSH2B; TSH2B.1
UniProt ID: (Human) Q96QV6, (Human) P0C0S8, (Human) Q96KK5, (Human) Q99878, (Human) P04908, (Human) P20671, (Human) P16104, (Human) P0C0S5, (Human) Q96A08, (Rat) Q00728, (Mouse) C0HKE5, (Mouse) Q8CGP6, (Mouse) C0HKE6, (Mouse) C0HKE1, (Mouse) C0HKE3, (Mouse) C0HKE4, (Mouse) P27661, (Mouse) P0C0S6, (Rat) P0C0S7, (Rat) Q00729
Entrez Gene ID: (Human) 221613, (Human) 8969, (Human) 85235, (Human) 8329, (Human) 8331, (Human) 8335, (Human) 3013, (Human) 3012, (Human) 3014, (Human) 3015, (Human) 255626, (Rat) 24828, (Mouse) 319167, (Mouse) 319168, (Rat) 680322, (Mouse) 319191, (Mouse) 319172, (Mouse) 319165, (Mouse) 319166, (Rat) 500987, (Mouse) 15270, (Mouse) 51788, (Rat) 58940, (Rat) 24829
DNA binding
structural constituent of chromatin
protein heterodimerization activity
protein binding
enzyme binding
damaged DNA binding
histone binding
chromatin-protein adaptor activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
chromatin DNA binding
nucleosomal DNA binding
DNA damage checkpoint
double-strand break repair via homologous recombination
DNA repair
chromatin organization
nucleosome disassembly
cellular response to DNA damage stimulus
spermatogenesis
negative regulation of cell proliferation
cerebral cortex development
heterochromatin assembly
UV-damage excision repair
cellular response to gamma radiation
cellular senescence
protein localization to site of double-strand break
protein localization to CENP-A containing chromatin
positive regulation of transcription from RNA polymerase II promoter
cellular response to estradiol stimulus
cellular response to insulin stimulus
nucleosome assembly
inflammatory response
plasminogen activation
sperm chromatin condensation
chromosome organization
mononuclear cell migration
double-strand break repair
response to ionizing radiation
positive regulation of DNA repair
protein K63-linked ubiquitination
positive regulation of double-strand break repair via homologous recombination
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support