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Invitrogen
Phospho-PKC zeta/lambda (Thr410, Thr403) Polyclonal Antibody
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Product Details
PA5-17837
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding pThr410 of human PKC zeta
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with endogenous levels of other PKC isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: atypical protein kinase C; nPKC-eta; nPKC-zeta; PKC-L; PRKCI; protein kinase C zeta subspecies; protein kinase C, zeta subspecies; Protein uPEP2; unnamed protein product
Gene Aliases: 14-3-3-zetaisoform; aPKCzeta; nPKC-eta; nPKC-zeta; PKC-L; PKC-ZETA; PKC2; Pkch; PKCL; Pkcz; PRKCL; r14-3-3; uORF2; zetaPKC
UniProt ID: (Human) P24723, (Human) Q05513, (Mouse) P23298, (Rat) Q64617, (Mouse) Q02956, (Rat) P09217
Entrez Gene ID: (Human) 5583, (Human) 5590, (Mouse) 18755, (Rat) 81749, (Mouse) 18762, (Rat) 25522
protein kinase activity
protein serine/threonine kinase activity
protein kinase C activity
calcium-independent protein kinase C activity
protein binding
ATP binding
enzyme binding
protein serine/threonine kinase inhibitor activity
small GTPase binding
translation regulator activity
protein serine kinase activity
protein serine/threonine kinase binding
calcium-dependent protein kinase C activity
insulin receptor substrate binding
potassium channel regulator activity
protein kinase binding
phospholipase binding
macromolecular complex binding
14-3-3 protein binding
microtubule cytoskeleton organization
positive regulation of cell-matrix adhesion
protein phosphorylation
cell surface receptor signaling pathway
long-term memory
positive regulation of cell proliferation
cell migration
peptidyl-serine phosphorylation
establishment of cell polarity
negative regulation of protein complex assembly
activation of protein kinase B activity
positive regulation of interleukin-10 production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
cellular response to insulin stimulus
intracellular signal transduction
positive regulation of phosphorylation
negative regulation of apoptotic process
positive regulation of T-helper 2 cell differentiation
negative regulation of insulin receptor signaling pathway
positive regulation of insulin receptor signaling pathway
vesicle transport along microtubule
positive regulation of synaptic transmission
positive regulation of protein transport
negative regulation of hydrolase activity
membrane depolarization
membrane hyperpolarization
long-term synaptic potentiation
positive regulation of ERK1 and ERK2 cascade
protein localization to plasma membrane
regulation of neurotransmitter receptor localization to postsynaptic specialization membrane
positive regulation of smooth muscle cell-matrix adhesion
neuron projection extension
positive regulation of excitatory postsynaptic potential
positive regulation of T-helper 2 cell cytokine production
signal transduction
positive regulation of macrophage derived foam cell differentiation
negative regulation of translation
positive regulation of translation in response to stress
cellular response to amino acid starvation
negative regulation of glial cell apoptotic process
positive regulation of keratinocyte differentiation
positive regulation of B cell receptor signaling pathway
positive regulation of glial cell proliferation
phospholipase C/protein kinase C signal transduction
positive regulation of protein localization to plasma membrane
regulation of bicellular tight junction assembly
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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