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Invitrogen

Phospho-PKC zeta/lambda (Thr410, Thr403) Polyclonal Antibody

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Phospho-PKC zeta/lambda (Thr410, Thr403) Polyclonal Antibody

Product Details

PA5-17837

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
View 3 publications 3 publications
Product Specifications

Species Reactivity

Human, Mouse, Non-human primate, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr410 of human PKC zeta
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Purification

Antigen affinity chromatography

Storage buffer

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_10986758

Product Specific Information

It is not recommended to aliquot this antibody.



This antibody is not cross-reactive with endogenous levels of other PKC isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: atypical protein kinase C; nPKC-eta; nPKC-zeta; PKC-L; PRKCI; protein kinase C zeta subspecies; protein kinase C, zeta subspecies; Protein uPEP2; unnamed protein product

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Gene Aliases: 14-3-3-zetaisoform; aPKCzeta; nPKC-eta; nPKC-zeta; PKC-L; PKC-ZETA; PKC2; Pkch; PKCL; Pkcz; PRKCL; r14-3-3; uORF2; zetaPKC

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UniProt ID: (Human) P24723, (Human) Q05513, (Mouse) P23298, (Rat) Q64617, (Mouse) Q02956, (Rat) P09217

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Entrez Gene ID: (Human) 5583, (Human) 5590, (Mouse) 18755, (Rat) 81749, (Mouse) 18762, (Rat) 25522

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Function(s)
protein kinase activity protein serine/threonine kinase activity protein kinase C activity calcium-independent protein kinase C activity protein binding ATP binding enzyme binding protein serine/threonine kinase inhibitor activity small GTPase binding translation regulator activity protein serine kinase activity protein serine/threonine kinase binding calcium-dependent protein kinase C activity insulin receptor substrate binding potassium channel regulator activity protein kinase binding phospholipase binding macromolecular complex binding 14-3-3 protein binding
Process(es)
microtubule cytoskeleton organization positive regulation of cell-matrix adhesion protein phosphorylation cell surface receptor signaling pathway long-term memory positive regulation of cell proliferation cell migration peptidyl-serine phosphorylation establishment of cell polarity negative regulation of protein complex assembly activation of protein kinase B activity positive regulation of interleukin-10 production positive regulation of interleukin-13 production positive regulation of interleukin-4 production positive regulation of interleukin-5 production cellular response to insulin stimulus intracellular signal transduction positive regulation of phosphorylation negative regulation of apoptotic process positive regulation of T-helper 2 cell differentiation negative regulation of insulin receptor signaling pathway positive regulation of insulin receptor signaling pathway vesicle transport along microtubule positive regulation of synaptic transmission positive regulation of protein transport negative regulation of hydrolase activity membrane depolarization membrane hyperpolarization long-term synaptic potentiation positive regulation of ERK1 and ERK2 cascade protein localization to plasma membrane regulation of neurotransmitter receptor localization to postsynaptic specialization membrane positive regulation of smooth muscle cell-matrix adhesion neuron projection extension positive regulation of excitatory postsynaptic potential positive regulation of T-helper 2 cell cytokine production signal transduction positive regulation of macrophage derived foam cell differentiation negative regulation of translation positive regulation of translation in response to stress cellular response to amino acid starvation negative regulation of glial cell apoptotic process positive regulation of keratinocyte differentiation positive regulation of B cell receptor signaling pathway positive regulation of glial cell proliferation phospholipase C/protein kinase C signal transduction positive regulation of protein localization to plasma membrane regulation of bicellular tight junction assembly
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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