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Invitrogen
IFT88 Polyclonal Antibody
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FIGURE: 1 / 7
IFT88 Antibody (PA5-18467) in ICC/IF
Immunocytochemistry analysis of IFT88 using IFT88 Polyclonal Antibody (Product # PA5-18467) in paraformaldehyde fixed HepG2 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL), showing nuclear and cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 µg/mL) followed by Alexa Fluor 488 secondary antibody (2 µg/mL).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-18467
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Dog,
Human,
Mouse
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide sequence (KKRIDEDDFADEE) corresponding to the C-terminus amino acids of IFT88 (aa 804-816).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Ammonium sulfate precipitation
Storage buffer
TBS, pH 7.3, with 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody is predicted to react with canine and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
Target Information
This gene encodes a member of the tetratrico peptide repeat family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HGNC:20606; intraflagellar transport 88 homolog; MGC26259; mutations in the mouse Tg737 gene cause polycystic kidney disease; polaris homolog; probe hTg737 (polycystic kidney disease, autosomal recessive); recessive polycystic kidney disease protein Tg737; recessive polycystic kidney disease protein Tg737 homolog; RP11-172H24.2; testicular tissue protein Li 93; tetratricopeptide repeat domain 10; tetratricopeptide repeat protein 10; Tg737 protein; tgN(Imorpk)737Rpw; TPR repeat protein 10; transgene insert site 737, insertional mutation, polycystic kidney disease; unnamed protein product
Gene Aliases: D13S1056E; DAF19; flexo; fxo; hTg737; orpk; polaris; TG737; Tg737Rpw; TgN737Rpw; TTC10
UniProt ID: (Human) Q13099, (Mouse) Q61371
Entrez Gene ID: (Human) 8100, (Mouse) 21821
eye development
kidney development
endothelial cell morphogenesis
liver development
cilium movement
Notch signaling pathway
smoothened signaling pathway
sperm axoneme assembly
spermatid nucleus elongation
determination of left/right symmetry
nervous system development
brain development
heart development
protein localization
epidermis development
organ morphogenesis
anterior/posterior pattern specification
dorsal/ventral pattern formation
spinal cord dorsal/ventral patterning
telencephalon development
lung development
forebrain development
pancreas development
cytoplasmic microtubule organization
response to fluid shear stress
intraciliary anterograde transport
epidermal stem cell homeostasis
intraciliary transport
regulation of odontogenesis of dentin-containing tooth
embryonic digit morphogenesis
positive regulation of insulin-like growth factor receptor signaling pathway
regulation of fat cell differentiation
positive regulation of cilium assembly
forebrain morphogenesis
negative regulation of epithelial cell proliferation
cardiac muscle cell differentiation
inner ear receptor stereocilium organization
limb development
regulation of feeding behavior
cilium morphogenesis
cardiac septum morphogenesis
lung vasculature development
heart formation
neural precursor cell proliferation
regulation of protein processing
cochlea development
regulation of cilium assembly
primary palate development
non-motile cilium assembly
regulation of autophagosome assembly
response to silicon dioxide
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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