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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
A suggested positive control is mouse brain tissue lysate.
PA5-20676 can be used with blocking peptide PEP-0794.
KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide -receptive H-2Kb.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ly49I; Ly49I receptor; LY49I1; lymphocyte antigen 49c; natural killer cell-associated antigen 2; T-cell surface glycoprotein Ly-49C; unnamed protein product
Gene Aliases: 5E6; Ly49c; Nk-2; NK-2.1; Nk2; Nk2.1
UniProt ID: (Mouse) Q64329
Entrez Gene ID: (Mouse) 16634
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