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Invitrogen
Brachyury Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-23405
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 350-400 of human Brachyury.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1.0 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: brachyury; brachyury protein; brachyury-like 2; brachyury-like 3; low ratio; protein T; RP11-459F1.1; T; T brachyury transcription factor; T, brachyury homolog
Gene Aliases: Bra; cou; D17Mit170; Low; Lr; me75; SAVA; T; T1; Tbxt; TFT; Tl2; Tl3
UniProt ID: (Mouse) P20293, (Human) O15178
Entrez Gene ID: (Mouse) 20997, (Human) 6862
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
sequence-specific DNA binding
RNA polymerase II sequence-specific DNA binding transcription factor binding
sequence-specific double-stranded DNA binding
negative regulation of transcription from RNA polymerase II promoter
mesoderm formation
cell fate specification
somitogenesis
heart morphogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
signal transduction
mesoderm development
anterior/posterior axis specification, embryo
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
cardiac muscle cell myoblast differentiation
primitive streak formation
vasculogenesis
neural plate morphogenesis
neural tube closure
penetration of zona pellucida
mesoderm migration involved in gastrulation
positive regulation of cell proliferation
anatomical structure morphogenesis
anterior/posterior pattern specification
notochord formation
signal transduction involved in regulation of gene expression
notochord development
post-anal tail morphogenesis
embryonic skeletal system development
cardiac muscle cell differentiation
bone morphogenesis
determination of heart left/right asymmetry
cellular response to retinoic acid
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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